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This mechanism becomes maladaptive in diabetes, however as hyperglycemia rise the expression and activity of sodium-glucose cotransporter (SGLT2) in the proximal tubule of the kidney

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Because the CellTox Green Dye can be added in a no-step format by adding the dye directly to cells at plating, the CellTox Green Cytotoxicity Assay can be performed prior to the GSH/GSSG-Glo Assay without changes to either protocol

Pregnancy is also a contraindication

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